Calmodulin and CaMKII in the sperm principal piece: evidence for a motility-related calcium/calmodulin pathway
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Both cyclic AMP (cAMP)/protein kinase A (PKA) and calcium (Ca(2+)) signaling pathways are known to be involved in the regulation of motility in mammalian sperm. Calmodulin (CaM) is a ubiquitous Ca(2+) sensor that has been implicated in the acrosome reaction. I... ...