The His-Pro-Phe motif of angiotensinogen is a crucial determinant of the substrate specificity of renin
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The amino acid sequence His-Pro-Phe as N-terminal residues 6-8 of the natural renin substrate, angiotensinogen, is conserved among species. We investigated whether this His-Pro-Phe motif functions as the determinant of the substrate specificity of renin. Mutan... ...
