Nef protein of human immunodeficiency virus type 1 binds its own myristoylated N-terminus
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HIV-1 Nef is a small protein (approx. 25 kDa) that is posttranslationally modified by myristoylation. To explain its complex activities, a 'Nef-cycle' is discussed, which postulates different molecular conformations of Nef. Using recombinant full-length non-my... ...