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Use of cryopreserved transiently transfected cells in high-throughput pregnane X receptor transactivation assay

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Cryopreserved, transiently transfected HepG2 cells were compared to freshly transfected HepG2 cells for use in a pregnane X receptor (PXR) transactivation assay. Assay performance was similar for both cell preparations; however, cryopreserved cells demonstrate... ...