Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk
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The strict spatio-temporal control of Rho GTPases is critical for many cellular functions, including cell motility, contractility, and growth. In this regard, the prototypical Rho family GTPases, Rho, Rac, and Cdc42 regulate the activity of each other by a sti... ...
