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Randomized Controlled Trial HIV clinical trials. 2006 Nov-Dec;7(6):285-90. doi: 10.1310/hct0706-285 0.02025

No virological failure in semen during properly suppressive antiretroviral therapy despite subtherapeutic local drug concentrations

有效的抗逆转录病毒治疗可抑制精液中的病毒复制尽管局部药物浓度低于治疗浓度 翻译改进

Selwyn H Lowe  1, Annemarie M J Wensing, Jacqueline A H Droste, Reinier W ten Kate, Suzanne Jurriaans, David M Burger, Jan C C Borleffs, Joep M A Lange, Jan M Prins

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  • 1 Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Centre, University of Amsterdam, Amsterdam. Lowe@LMIB.azM.nl
  • DOI: 10.1310/hct0706-285 PMID: 17197376

    摘要 Ai翻译

    Purpose: The aim of the study was to investigate whether drug resistance occurs earlier in seminal than in blood plasma with the use of such HAART regimens, of which only the two NRTIs achieve therapeutic concentrations in seminal plasma. Method: Seminal and blood plasma of 12 patients, for 48-96 weeks on suppressive first-line therapy with ... ...点击完成人机验证后继续浏览
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    期刊名:Hiv clinical trials

    缩写:HIV CLIN TRIALS

    ISSN:1528-4336

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    No virological failure in semen during properly suppressive antiretroviral therapy despite subtherapeutic local drug concentrations