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Paired helical filaments contain small amounts of cholesterol, phosphatidylcholine and sphingolipids

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By using qualitative and quantitative high-performance thin layer chromatography (hpTLC) we found lipids associated with purified Alzheimer's (AD) paired helical filaments (PHF) in an amount of 1.4+/-0.2% of the total anhydrous mass. Compared to normal brain t... ...