Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice
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Cathepsin B (CTSB) and cathepsin L (CTSL) are two widely expressed cysteine proteases thought to predominantly reside within lysosomes. Functional analysis of CTSL in humans is complicated by the existence of two CTSL-like homologs (CTSL and CTSL2), in contras... ...
