Cathepsins L and S are not required for activation of dipeptidyl peptidase I (cathepsin C) in mice
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The cysteine protease dipeptidyl peptidase I (DPPI) activates granule-associated immune-cell serine proteases. The in vivo activator of DPPI itself is unknown; however, cathepsins L and S are candidates because they activate pro-DPPI in vitro. In this study, w... ...