Adaptation of the behaviour of an aspartic proteinase inhibitor by relocation of a lysine residue by one helical turn
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In addition to self-inhibition of aspartic proteinase zymogens by their intrinsic proparts, the activity of certain members of this enzyme family can be modulated through active-site occupation by extrinsic polypeptides such as the small IA3 protein from Sacch... ...
