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Journal of medical genetics. 2006 Jun;43(6):e29. doi: 10.1136/jmg.2005.032839 Q23.72025

The cystic fibrosis transmembrane conductance regulator (Cftr) modulates the timing of puberty in mice

囊性纤维化跨膜传导调节器(Cftr)可调节小鼠青春期的时间 翻译改进

R Jin, C A Hodges, M L Drumm, M R Palmert

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DOI: 10.1136/jmg.2005.032839 PMID: 16740913

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Background: Delayed puberty is common among individuals with cystic fibrosis (CF) and is usually attributed to chronic disease and/or poor nutrition. However, it has recently been recognised that pubertal delay can occur even in the setting of good nutritional and clinical status. This finding, along with evidence that Cftr is expressed in rat brain, human hypothalamus, and a gonadotropin releasing hormone secreting cell line... ...点击完成人机验证后继续浏览
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期刊名:Journal of medical genetics

缩写:J MED GENET

ISSN:0022-2593

e-ISSN:1468-6244

IF/分区:3.7/Q2

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The cystic fibrosis transmembrane conductance regulator (Cftr) modulates the timing of puberty in mice