Ecto- and cytosolic 5'-nucleotidases in normal and AMP deaminase-deficient human skeletal muscle
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In skeletal muscle, adenosine monophosphate (AMP) is mainly deaminated by AMP deaminase. However, the C34T mutation in the AMPD1 gene severely reduces AMP deaminase activity. Alternatively, intracellular AMP is dephosphorylated to adenosine via cytosolic AMP 5... ...
