A role for the protein phosphatase 2B in altered hippocampal synaptic plasticity in the aged rat
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Synaptic plasticity following NMDA application on hippocampal slices from young (3-5 months) and aged (24-27 months) rats was compared. In young rats, NMDA (20 microM) induced opposite effects depending on the duration of the application. A short (1 min) or lo... ...