Varicella-zoster virus IE63 protein represses the basal transcription machinery by disorganizing the pre-initiation complex
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Using transient transfection assays, regulation properties of varicella-zoster virus (VZV)-encoded IE63 protein were analyzed on several VZV immediate early (ORF4), early (ORF28) and late (ORF67) promoters. IE63 was shown to repress the basal activity of most ... ...
