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GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor

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The androgen receptor (AR) mediates transactivation of target genes by acting as a dimer in which its amino-terminal domain (AR-NTD) interacts with its carboxyl-terminal, ligand-binding domain (AR-LBD) (N/C interaction). Here we assessed if and how AR N/C inte... ...