Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts
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The glyoxalase system consisting of glyoxalase I (GloI) and glyoxalase II (GloII) constitutes a glutathione-dependent intracellular pathway converting toxic 2-oxoaldehydes, such as methylglyoxal, to the corresponding 2-hydroxyacids. Here we describe a complete... ...
