Effect of active site-inactivated factor VIIa on ischaemia/reperfusion injury in a porcine flap model
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In free flap surgery, restored blood flow following a lengthy ischaemic period may lead to necrosis as a result of ischaemia/reperfusion (IR) injury. This injury comprises both proinflammatory and prothrombotic events, where the tissue factor/factor VIIa compl... ...
