Functional characterization of the postulated intramolecular sphingolipid activator protein domain of human acid sphingomyelinase
{{output}}
Degradation of membrane-bound sphingomyelin to phosphorylcholine and ceramide is catalyzed by the water-soluble lysosomal acid sphingomyelinase (A-SMase). The presence of sphingolipid activator proteins (Saps: saposins A-D; GM2 activator) is not essential to m... ...
