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European urology. 2004 Aug;46(2):188-94. doi: 10.1016/j.eururo.2004.04.020 Q125.22024

Erectile and urinary dysfunction after radical prostatectomy for prostate cancer in Quebec: a population-based study of 2415 men

前列腺癌根治术后勃起功能障碍和排尿功能障碍的流行病学研究:蒙特利尔2415例患者分析 翻译改进

Pierre I Karakiewicz  1, Simon Tanguay, Michael W Kattan, Mostafa M Elhilali, Armen G Aprikian

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  • 1 Department of Surgery (Urology), McGill University, Montreal, Quebec, Canada. pkarak@earthlink.net
  • DOI: 10.1016/j.eururo.2004.04.020 PMID: 15245812

    摘要 Ai翻译

    Objective: To assess and quantify urinary and sexual function outcomes from a large scale cohort of Canadian men treated for localized prostate cancer.

    Methods: A self-administered survey focusing on erectile (ED) and urinary dysfunction (UD) was completed by 2415 of 4546 men (response rate 53.1%) treated with prostatectomy for prostate cancer in the Province of Quebec between 1988 and 1996. The time between treatment and survey completion ranged from 17 months to 8.5 years.

    Results: After prostatectomy, of 2227 men without ED before surgery, erections of adequate firmness for intercourse were reported by 25%. ED rate increased with age and ranged from 55% in men aged <60 years to 85% in men 75 years or older. Of all, 19.1% reported ED treatment. ED rate was significantly related to UD severity. Severe UD, quantified as urinary leakage exceeding one tablespoon, was reported by 6.6%. Severe UD rate ranged from 4% in men aged <60 years to 10% in men 75 years or older. Strictures were reported by 16.3% and were associated with a two-fold increase in severe UD rate (p<0.001). Finally, age and socioeconomic status represented important predictor variables in univariate and multivariate regression models.

    Conclusion: ED rate of 75% and severe UD rate of 6.6% could be anticipated after RP. These outcomes are similar to unselected large scale, patient reported outcomes from the United States.

    Keywords:Erectile Dysfunction; Urinary Dysfunction; Radical Prostatectomy; Prostate Cancer

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    期刊名:European urology

    缩写:EUR UROL

    ISSN:0302-2838

    e-ISSN:1873-7560

    IF/分区:25.2/Q1

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    Erectile and urinary dysfunction after radical prostatectomy for prostate cancer in Quebec: a population-based study of 2415 men