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Unusual Guanylyl Cyclases and cGMP Signaling in Dictyostelium discoideum

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cGMP is used as a second messenger in many eukaryotes. cGMP signaling requires at least three components: Guanylyl cyclases synthesize cGMP from GTP. Specific cGMP-binding proteins propagate the signal, usually by phosphorylation of their target proteins. Fina... ...