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Review Pharmaceutical research. 2004 Mar;21(3):389-93. doi: 10.1023/B:PHAM.0000019289.61978.f5 Q14.32025

Cell penetrating peptides in drug delivery

药物传输中的细胞穿膜肽 翻译改进

Eric L Snyder  1, Steven F Dowdy

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  • 1 Howard Hughes Medical Institute and Department of Cellular & Molecular Medicine, University of California at San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0686, USA.
  • DOI: 10.1023/B:PHAM.0000019289.61978.f5 PMID: 15070086

    摘要 Ai翻译

    Protein transduction domains (PTDs) are small cationic peptides that can facilitate the uptake of large, biologically active molecules into mammalian cells. Recent reports have suggested that PTDs may be able to mediate the delivery of cargo to tissues throughout a living organism. Such technology could eliminate the size restrictions on usable drugs, enabling previously unavailable large molecules to modulate in vivo biology and alleviate disease. In this... ...点击完成人机验证后继续浏览
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    期刊名:Pharmaceutical research

    缩写:PHARM RES-DORDR

    ISSN:0724-8741

    e-ISSN:1573-904X

    IF/分区:4.3/Q1

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    Cell penetrating peptides in drug delivery