Suboptimal action of NF-kappaB in Fanconi anemia cells results from low levels of thioredoxin
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Electrophoretic mobility shift assays (EMSA) revealed that under standard cell culture conditions NF-kappaB was induced in Fanconi anemia fibroblasts in contrast to control cells. Dithiothreitol, a potent synthetic redox potential-delivering compound, when add... ...