Thermodynamic analysis of the dissociation of the aldolase tetramer substituted at one or both of the subunit interfaces
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The fructose-1,6-bis(phosphate) aldolase isologous tetramer tightly associates through two different subunit interfaces defined by its 222 symmetry. Both single- and double-interfacial mutant aldolases have a destabilized quaternary structure, but there is lit... ...
