Trichostatin A and structurally related histone deacetylase inhibitors induce 5-lipoxygenase promoter activity
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5-Lipoxygenase (5-LO) mRNA expression in Mono Mac 6 cells is induced by the histone deacetylase inhibitor trichostatin A (TsA). In order to study the effects of TsA and several structurally related compounds such as MD85, D237 and M232 on 5-LO promoter activit... ...
