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Treatment of bleeding in patients with platelet disorders: is there a place for recombinant factor VIIa?

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The mechanism of action of recombinant factor VIIa (rFVIIa), i.e. increased thrombin generation on the membrane of activated platelets, as well as the results from in vitro and ex vivo models of thrombocytopenia or inherited thrombocytopathia may support some ... ...