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Suppression of inflammation and joint destruction in rheumatoid arthritis may require a concerted action of Th2 cytokines

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A predominance of T-helper 1 (Th1) activity and a lack of Th2 activity has been documented in the inflamed joints of patients with rheumatoid arthritis (RA). This imbalance is suggested to contribute to activation of, particularly, inflammatory macrophages and... ...