Analysis of a role for p16/CDKN2 expression and methylation patterns in human oral squamous cell carcinoma
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The p16/CDKN2 (cyclin dependent kinase number 2) gene is known to be one of the negative regulators of the cell cycle. Aberrant 5'CpG island methylation is one of the most important mechanisms of p16/CDKN2 gene promoter region alteration. We studied 8 oral squ... ...
