Development and use of a gene promoter-based screen to identify novel inhibitors of cyclooxygenase-2 transcription
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Cyclooxygenase-2 (COX-2) is a recognized target for cancer prevention and possibly treatment. To identify novel inhibitors of COX-2, we developed a high throughput reporter gene assay that utilizes a region of the human COX-2 promoter to drive luciferase expre... ...
