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Anterior neural tube malformations induced after all-trans retinoic acid administration in white rat embryos. I. Macroscopical observations

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For this study all-trans-retinoic acid was administered in pregnant white rats in their "prima gravida" pregnancy. Rats were divided in five groups. The first three groups were treated with 20 mg R.A./kg b.w. at several gestational days. The fourth group was t... ...