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Cancer research. 1999 Jan 1;59(1):107-14. Q116.62025

Enhancement of tumor radioresponse in vivo by gemcitabine

吉西他滨增敏体内肿瘤放射效应 翻译改进

L Milas  1, T Fujii, N Hunter, M Elshaikh, K Mason, W Plunkett, K K Ang, W Hittelman

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  • 1 Department of Experimental Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
  • PMID: 9892194

    摘要 Ai翻译

    Gemcitabine, 2'2'-difluoro-2'-deoxycytidine, is an inhibitor of DNA synthesis and has been shown previously in vitro and in vivo to enhance the cytotoxic activity of radiation as well as some chemotherapeutic agents. Because gemcitabine has shown clinical activity on its own in several solid tumors traditionally treated with radiotherapy, it was of interest to optimize the combination of gemcitabine and radiation. To determine the optimal gemcitabine dose ... ...点击完成人机验证后继续浏览
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    期刊名:Cancer research

    缩写:CANCER RES

    ISSN:0008-5472

    e-ISSN:1538-7445

    IF/分区:16.6/Q1

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    Enhancement of tumor radioresponse in vivo by gemcitabine