Current findings show that adenylate cyclases comprise a heterogeneous multigene family, members of which are variously regulated by the alpha and beta gamma subunits of G proteins, by Ca2+ and by protein kinases. In the CNS, individual isoforms of adenylate cyclase are expressed discretely in select regions of the brain. At the subcellular level, adenylate cyclases can be concentrated into dendritic spines, thereby increasing their susceptibility to multiple regulatory influences. Altogether, such findings greatly expand knowledge of the potential role of this archetypical signaling system in the modulation of neuronal function.
Review Trends in neurosciences. 1995 Dec;18(12):536-42. doi: 10.1016/0166-2236(95)98375-9 Q114.62024
Adenylate cyclases: critical foci in neuronal signaling
腺苷酸环化酶：神经信号转导的关键节点 翻译改进
作者单位 +展开
作者单位
DOI: 10.1016/0166-2236(95)98375-9 PMID: 8638294
摘要 Ai翻译
Keywords：adenylate cyclases; neuronal signaling
相关内容
-
Plant adenylate cyclases
植物腺苷酸环化酶
Journal of receptor and signal transduction research. 2008;28(6):531-42.
-
Adenylate cyclases involvement in pathogenicity, a minireview
环核苷酸环化酶与致病性之间的关系——综述
Roumanian archives of microbiology and immunology. 2013 Jan-Mar;72(1):63-86.
-
Demonstration of distinct forms of testicular adenylate cyclases associated with germinal and Leydig cell fractions
不同形式的睾丸腺苷酸环化酶的相关实验验证（与生殖细胞和Leydig细胞组分有关）
Biochimica et biophysica acta. 1982 Aug 6;717(2):183-9.
-
Plant-activated bacterial receptor adenylate cyclases modulate epidermal infection in the Sinorhizobium meliloti-Medicago symbiosis
苜蓿根瘤菌Sinorhizobium meliloti中的植物激活的细菌受体腺苷酸环化酶调节表皮感染
Proceedings of the National Academy of Sciences of the United States of America. 2012 Apr 24;109(17):6751-6.
-
Adenylate and guanylate cyclases in Tetrahymena
托里索马原虫腺苷酸环化酶和鸟苷酸环化酶
Progress in molecular and subcellular biology. 1996:17:40-60.
-
Adenylate and guanylate cyclases of cecropia silkmoth fat body
家蚕脂肪体中的腺苷酸环化酶和鸟苷酸环化酶
Journal of insect physiology. 1976;22(12):1635-40.
-
Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle
β1、β2和β3肾上腺素受体介导的内肛门括约肌平滑肌松弛中腺苷酸环化酶和鸟苷酸环化酶的作用
The Journal of pharmacology and experimental therapeutics. 2004 Mar;308(3):1111-20.
-
Adenylate cyclases in two populations of membranes purified from neuroblastoma X glioma hybrid (NG 108-15) cells
神经母细胞瘤-glioma杂交(NG 108-15)细胞两组膜中腺苷酸环化酶的分离纯化
Journal of cyclic nucleotide and protein phosphorylation research. 1985;10(6):565-78.
