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Structural studies on DNA-binding drugs: crystal structure and molecular dynamics studies of triazoloacridinones

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Structural and conformational studies on two 8-substituted triazoloacridinone antitumor agents, C1295 and C1303, have been carried out to compare the conformation of the (aminoalkyl)amino side chain and the effect of C-8 substitution. Crystal data for 5-[2-(di... ...