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Structures of histamine H1-receptor antagonists derived from the cimetidine group of histamine H2-receptor antagonists

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The crystal and molecular structures of ten compounds with strong structural resemblances to the cimetidine group of histamine H2-receptor antagonists, but exhibiting selective H1-receptor antagonist activity, (1)-(7), or H1 and H2 activity (8)-(10), have been... ...