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Clinical Trial Annals of allergy. 1990 Mar;64(3):300-5.

Multicenter, double-blind, placebo-controlled trial of triamcinolone acetonide nasal aerosol in the treatment of perennial allergic rhinitis

倍氯松鼻喷雾剂治疗常年性变态反应性鼻炎的多中心双盲安慰剂对照临床试验 翻译改进

S Spector  1, E Bronsky, P Chervinsky, G Lotner, J Koepke, J Selner, D Pearlman, D Tinkelman, S Weakley, V Alderfer, et al.

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  • 1 Department of Clinical Research, Rorer Central Research, Horsham, PA 19044.
  • PMID: 2178497

    摘要 Ai翻译

    In a double-blind study involving 205 patients with perennial allergic rhinitis, statistically significantly greater symptomatic improvements were evident following the administration of 200 micrograms/day triamcinolone acetonide aerosol than following placebo. These improvements were evident as early as week 1 and were sustained throughout the 12-week study. They were accompanied by greater reductions in nasal eosinophils. Triamcinolone acetonide aerosol was well tolerated and had no effect on serum cortisol levels.

    Keywords:allergic rhinitis; placebo-controlled trial

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    Multicenter, double-blind, placebo-controlled trial of triamcinolone acetonide nasal aerosol in the treatment of perennial allergic rhinitis