A peptide-polysaccharide, ABAB showing immunological activity was isolated from Achyeanthes bidentata Bl. It was shown to be homogeneous by HPLC and optical rotation analysis. Its molecular weight was estimated to be 2.3 x 10(4). It composed of D-glucuronic acid, D-galactose, D-galacturonic acid, L-arabinose and L-rhamnose in molar ratio of 12:2:3:1:1. Reduction of carboxyl groups, methylation analysis, periodate oxidation, Smith degradation and IR analysis showed that ABAB possesses a main chain composed of (1----4)-D-glucuronic acid and (1----4)-D-galacturonic acid residues. The non-reducing terminal residues in the side chains were L-arabinose and L-rhamnose. ABAB contained 24.1% of peptides composed of glycine, glutamic acid, aspartic acid and serine.
Yao xue xue bao = Acta pharmaceutica Sinica. 1990;25(7):526-9. 0.02024
[Chemical studies on polysaccharide of Achyeanthes bidentata]
牻牛儿苗多糖的化学研究 翻译改进
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PMID: 2085130
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Keywords:chemical studies
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