Binding characteristics of human hybridoma IgG and IgM rheumatoid factors: influence of IgG isotype and carbohydrate content
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The interaction of human monoclonal rheumatoid factors (RF) with the Fc portion of IgG is complex. We have investigated the influence of the nature of the antigen (Fc) on the binding of hybridoma-generated RF derived from patients with rheumatoid arthritis or ... ...