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Clinical Trial British journal of clinical pharmacology. 1992 Apr;33(4):445-8. doi: 10.1111/j.1365-2125.1992.tb04065.x Q23.02025

Inhibition of histamine-induced nasal obstruction by cetirizine in allergic rhinitis

西替利嗪对过敏性鼻炎患者组胺致鼻阻塞的抑制作用 翻译改进

G Braunstein  1, F Malaquin, I Fajac, M Melac, N Frossard

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  • 1 UFR Cochin-Port Royal, Paris, France.
  • DOI: 10.1111/j.1365-2125.1992.tb04065.x PMID: 1349494

    摘要 Ai翻译

    This double-blind randomized crossover placebo-controlled study was designed to assess objectively the nasal antihistamine effect of cetirizine in patients with allergic rhinitis and control subjects. Nasal challenge was performed by nebulization of increasing doubling doses of histamine (0; 0.04 to 1.28 mg/nostril) in six patients with allergic rhinitis and six control subjects on cetirizine (2 x 10 mg daily for 3 days) or placebo. Sneezings were counted ... ...点击完成人机验证后继续浏览
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    期刊名:British journal of clinical pharmacology

    缩写:BRIT J CLIN PHARMACO

    ISSN:0306-5251

    e-ISSN:1365-2125

    IF/分区:3.0/Q2

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    Inhibition of histamine-induced nasal obstruction by cetirizine in allergic rhinitis